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KMID : 0545119980080030287
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Journal of Microbiology and Biotechnology
1998 Volume.8 No. 3 p.287 ~ p.290
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Acarbose Effect for Dexran Synthesis, Acceptor and Disproportionation Reactions of Leuconostoc mesenteroides B-512 FMCM Dextransucrase
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Kim, Do Man
Park, Kwan Hwa/John F.Robyt
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Abstract
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Acarbose effectively inhibited the synthesis of dextran, and the inhibition pattern was a noncompetitive type with a K_i value of 1.35 mM. It also inhibited the disproportionation reaction of dextransucrase with isomaltotriose and decreased the efficiency of the maltose acceptor reaction. Increased concentration of dextransucrase or maltose in reaction digests, however, decreased the degree of inhibition by acarbose.
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